Notebook
November 11th, 2007 by Richard Brassaw

Just a few years ago most scientists believed that the human adult does not produce new brain cells. What is now known is, yes, adults do generate new brain cells and that the area of the brain that creates the new cells is called the hippocampus. (The hippocampus plays a part in memory and spatial [...]

November 10th, 2007 by Richard Brassaw

Stress activates a neurochemical response in the brain that triggers a release of gluocorticoids, which is known not to be good for you cognitively. High levels of gluocorticoids are associated with such psychiatric conditions as schizophrenia, post traumatic stress disorder (PTSD), and Alzheimer’s disease. High levels of glucorticoids can cause damage brain nerve cells by [...]

November 9th, 2007 by Richard Brassaw

A characteristic often associated with Parkinson’s disease is dyskinesias, which is a spastic (or repetitive) motion. Dyskinesia is sometimes caused by the long-term use of medication to help control the disease like levodopa, or L-dopa. The drug dextromethorphan is currently used to treat dyskinesias. Dextromethorphan is a drug used in to suppress coughs in cold and flu [...]

November 8th, 2007 by Richard Brassaw

The current treatment for depression is most often a Selective Serotonin Reuptake Inhibitors (SSRIs), which helps make serotonin available to help manage mood and stress. The question is why SSRIs work better for some than others. A study done 10 years ago suggested that women respond better to SSRI treatment than men. Another study found that pre-menopausal women may also [...]

November 7th, 2007 by Richard Brassaw

Cognitive health has been added to the risk associated with obesity caused disorders. Researchers have convincing evidence that dietary practices throughout adulthood are important contributors to age related cognitive decline and dementia risk. Adults with diabetes are especially sensitive to the foods they eat with respect to cognitive function. Specifically, an adult with diabetes will [...]

November 6th, 2007 by Richard Brassaw

Although marijuana itself has shown no clinical benefit for the treatment of depression, University of Irvine researchers have shown that one of its active ingredients produces antidepressant effects. The brain naturally produces the enzyme anandamide, which is nicknamed the ‘bliss molecule’ because of its similarities to the active ingredient in marijuana and its anti-depressant qualities. The [...]

November 5th, 2007 by Richard Brassaw

Most current theories of how we form long-term memories is that they are encoded in our brain by changes in the connections between neurons, which would not allow them to be erased chemically. Recent research contradicts that theory by suggesting the enzyme PKMzeta, may actually be required to sustain memories. By targeting, new therapies could [...]

November 4th, 2007 by Richard Brassaw

A Mount Sinai study has linked Alzheimer’s disease, kidney disease, diabetes, insulin resistance, and inflammation to advanced glycation end products (AGEs). AGE naturally occurs highest in animal products that are grilled, fried, or broiled (i.e. meats and cheeses). Researchers are alarmed at how AGE consumption correlates with the current trends of disease epidemics. They understand that the concept of food-related [...]

November 3rd, 2007 by Richard Brassaw

For 2 years, Dr Pasinetti, at Mount Sinai, screened more than 1,500 commercially available drugs for possible use in the battle against Alzheimer’s disease and cognitive impairment. What Pasinetti was specifically looking for was a drug that would stop the production of beta-amyloid, which is currently considered a critical factor for the development of Alzheimer’s [...]

November 2nd, 2007 by Richard Brassaw

A lot of patients are misdiagnosed as having Alzheimer’s disease, when they actually have frontotemporal dementia (FTD). Patients who are misdiagnosed are hospitalized and receive drugs for the wrong disease. Early diagnosis of FTD can have a tremendous impact on the patients and their family members–1/3 of FTD patients have a family history of a [...]