Notebook
April 20th, 2008 by Richard Brassaw

Dr. Thomas Montine, University of Washington, autopsied the brains of 3,400 men and women who had experienced cognitive decline and dementia.

45% of the risk for dementia was associated with pathologic changes of Alzheimer’s disease.
10% of dementia risk was associated with Lewy bodies (neocortical structural changes that indicate a degenerative brain disease known as Lewy Body [...]

April 19th, 2008 by Richard Brassaw

Recent studies have linked depression with Alzheimer’s disease. The question is if the depression is a result of the Alzheimer’s or a the cause of it.
Robert S. Wilson, PhD, Rush University Medical Center, Chicago, and colleagues studied 917 older Catholic nuns, priests, and monks–all of which were free from signs of dementia.
At the beginning of the [...]

April 18th, 2008 by Richard Brassaw

As baby-boomers become senior-boomers arthritis is projected to increase by 40%–affecting 67 million Americans–in the next 2 decades. At issue is improving and managing arthritis pain.
Leigh Callahan, PhD, Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, evaluated the basic 8-week Arthritis Foundation Exercise Program. The study showed:

The exercise program is suitable for every fitness [...]

April 17th, 2008 by Richard Brassaw

A person who suffers from Parkinson’s disease has a depletion of dopaminergic neurons. As a result there is a lack of dopamine in the body, which causes chronic and progressive symptoms including tremors, stiff muscles, and slow movement.
Dr. Anita Hall, Department of Live Sciences, Imperial College, London, and colleagues, used mouse models to examine the [...]

April 16th, 2008 by Richard Brassaw

ALS (amyotrophic lateral sclerosis), better known as Lou Gehrig’s disease, may be caused by leaky blood vessels that lose their ability to protect the spinal cord from toxins.
Berislav Zlokovic, MD, PhD, University of Rochester Medical Center, has developed over the last 15 years a view that the vascular system plays a central role in many [...]

April 15th, 2008 by Richard Brassaw

Why are more women, than men, diagnosed with chronic pain, chronic fatigue, and fibromyalgia? Approximately, 94% of people with chronic fatigue report muscle pain. Nearly, 75% of people reporting chronic widespread musculoskeletal pain report having fatigue. Women are the majority of patients reporting these symptoms.
Katheleen Sluka, PhD, professor Graduate Program in Physical Therapy and Rehabilitation [...]

April 14th, 2008 by Richard Brassaw

Traditional thinking has been that degenerative discs were primarily the result of handling heavy materials, postural loading, and vehicular vibration. There is now evidence that challenges that traditional thinking.
Michele Crites-Battié, faculty of Rehabilitation Medicine, University of Alberta, studied 147 pairs of identical twins, and 153 pairs of fraternal male twins, to determine what role occupational workloads [...]

April 13th, 2008 by Richard Brassaw

Current research indicates that there may be a link between developing diabetes in middle age and developing Alzheimer’s disease later in life.
Elina Rönnemaa, MD, Uppsala University, Uppsala, Sweden, reports on a study of 2,269 men in Sweden who, at 50, were tested for diabetes. During an average follow up of 32 years, 4½ percent of the participants were [...]

April 12th, 2008 by Richard Brassaw

Researchers move one step closer to understanding the process of Alzheimer’s disease.
One of the key areas of research for Alzheimer’s is amyloid beta and the plaque that it forms. Researchers believe that a process called endocytosis is involved in the increase of amyloid beta.
John Cirrito, PhD, research instructor in neurology, Washington University School of Medicine, [...]

April 11th, 2008 by Richard Brassaw

The European medicines regulator (EMEA) warned in 2007 that a newer diabetes drug, rosigilazone, should not be given to patients with a history of a heart attack, or patients with ischaemic heart, or peripheral arterial, diseases. Rosigiltazone and a similar medication, pioglitazone, belong to a class of drug known as glitazones.
Recently, the British Drug and [...]