
The origins of Alzheimer’s disease is thought to be the result of A-beta peptide (Alzheimer’s peptide) when it clumps together in the brain and forms long fibrils. Whether it is the protein clumps or the fibrils that kill brain neurons is still being debated.
Nikolaus Grigorieff, biophysicist, Brandeis University, along with researchers at Leibniz Institut, Jena, [...]
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Men and women differ on their risk of developing Alzheimer’s disease.
French researchers studied nearly 7,000 people over 65 years from the general population of 3 French cities. None of the subjects had dementia, but 4 out of 10 had mild cognitive impairment at the onset of the study. At 2 and 4 years the participants [...]
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Why diabetic patients are more likely to develop Alzheimer’s disease has not been understood. Researchers believe they may have identified the diabetes - Alzheimer’s connection.
David R. Schubert, PhD, professor Cellular Neurobiology Laboratory, Salk Institute for Biological Studies, reports that blood vessels in the brain of young diabetic mice are damaged by the interaction of elevated blood [...]
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Dementia is an umbrella term used to describe various cognitive degenerative diseases. A common form of dementia is Alzheimer’s disease. A relatively rare hereditary form of dementia is frontotemporal dementia (FTD) with parkinsonism-17. Both of these forms of dementia share a common pathology–an over accumulation of tau proteins, which form tangled lesions in the brain’s neurons [...]
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Every year over 200 million are anesthetized while undergoing surgery. A concern has been if the widely used anesthetic desflurane contributes to increased production of amyloid-beta protein (an indicator of Alzheimer’s disease.
Researchers Bin Zhang, Yuanlin Dong, Rudolph Tanzi, Zhongcong Xie, Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital/Harvard Medical School, [...]
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A new report shows that there is a link between the early onset of Alzheimer’s disease and heavy smoking and drinking.
Ranjan Duara, MD, Wien Center for Alzheimer’s Disease, Mount Sinai Medical Center, Miami Beach, Florida, studied 938 people age 60 and older. All participants had been diagnosed with possible/probable Alzheimer’s disease. Information of the participant’s [...]
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Dr. Thomas Montine, University of Washington, autopsied the brains of 3,400 men and women who had experienced cognitive decline and dementia.
45% of the risk for dementia was associated with pathologic changes of Alzheimer’s disease.
10% of dementia risk was associated with Lewy bodies (neocortical structural changes that indicate a degenerative brain disease known as Lewy Body [...]
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Recent studies have linked depression with Alzheimer’s disease. The question is if the depression is a result of the Alzheimer’s or a the cause of it.
Robert S. Wilson, PhD, Rush University Medical Center, Chicago, and colleagues studied 917 older Catholic nuns, priests, and monks–all of which were free from signs of dementia.
At the beginning of the [...]
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Researchers move one step closer to understanding the process of Alzheimer’s disease.
One of the key areas of research for Alzheimer’s is amyloid beta and the plaque that it forms. Researchers believe that a process called endocytosis is involved in the increase of amyloid beta.
John Cirrito, PhD, research instructor in neurology, Washington University School of Medicine, [...]
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For some time the Holy Grail of Alzheimer’s disease was thought to be a medication to clear beta-amyloid plaques from the brain, but current research suggest that isn’t going to be enough.
An study by the University of California, Irvine, has been testing an Alzheimer’s drug designed to clear the beta-amyloid plaques. Unfortunately, clearing the plaques [...]
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